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Proteomics samples of human cancer biopsies were combined to derive an atlas of protein–protein associations for human tissues. Differences between tissues are not strongly driven by gene expression but could, in part, be due to tissue-specific subcellular components and processes.
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References
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This is a summary of: Laman Trip, D. S. et al. A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes. Nat. Biotechnol. https://doi.org/10.1038/s41587-025-02659-z (2025).
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A protein association atlas for human tissues.
Nat Biotechnol (2025). https://doi.org/10.1038/s41587-025-02692-y
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DOI: https://doi.org/10.1038/s41587-025-02692-y
